Functional imaging of brain networks for speaking
Srikantan Nagarajan, Ph.D.
Professor, Department of Radiology and Biomedical Imaging
Director, Biomagnetic Imaging Laboratory
University of California-San Francisco
Speaking is a uniquely human ability vital to our social interactions; its breakdown can have profound consequences one’s quality of life. In this talk, I will review studies from our research group that involve flexible real-time speech feedback psychophysics, advanced magnetoencephalography (MEG) based imaging and navigated transcranial magnetic stimulation (nTMS) during speaking. At first, I will introduce problems in imaging with MEG that we have overcome with probabilistic graphical modeling algorithms. I will then highlight how we use MEG, and nTMS, to characterize the intricate dynamics of neural activity associated with syllable sequence reproduction and auditory feedback processing during speaking. Finally, I will discuss how the impact of these findings on computational models for speech motor control.